Solubilization of an Adenosine Uptake Site in Brain
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چکیده
منابع مشابه
Adenosine uptake sites in brain: regional distribution of putative subtypes in relationship to adenosine A1-receptors.
Adenosine uptake sites have been characterized and localized in guinea pig and pointer dog brain by in vitro autoradiography, using as probes 3H-nitrobenzylthioinosine (3H-NBI) and the recently available 3H-dipyridamole (3H-DPR). In guinea pig brain and, to a lesser extent, in pointer dog brain, 3H-DPR was found to label more high-affinity binding sites than 3H-NBI and NBI inhibited 3H-DPR bind...
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15 صفحه اولAdenosine uptake sites in rat brain: identification using [3H]nitrobenzylthioinosine and co-localization with adenosine deaminase.
The binding characteristics of [3H]nitrobenzylthioinosine ([3H]NBI) to rat brain membrane preparations was examined, and the autoradiographic distribution of this ligand in brain sections was compared with the immunohistochemical localization of adenosine deaminase (ADA). It was found that [3H]NBI labels sites for which adenosine has far higher affinity than do other nucleosides, that these sit...
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ژورنال
عنوان ژورنال: Journal of Neurochemistry
سال: 1985
ISSN: 0022-3042,1471-4159
DOI: 10.1111/j.1471-4159.1985.tb04028.x